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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ee457262ed74bc03be5628becb1ee58b202b16bf9451e6dbddb5dcdc8ca4c1e' 
  AND token = 'i5tG4ZM7DGQjHu6nd5BYsEssv43zT+4NI6FIKvyzKN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}