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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353658793c0a8840b216779ee615a1f9962538051ea0f37fff39f60ec4687eae' 
  AND token = 'LNklviyCqkjM0NigI9qmMunBF2UIF7GapJKnv9g8jpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}