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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '621c777a78445d4b7e1595347b0e8dd80ee8e714b56e40d9c4e60d38dbff5885' 
  AND token = 'yRKrmRQ52QP/IaLFkXKx21tcGcAEDWEq3Ukc8nML3AE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}