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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '339e4a2f765229e8e9a03959361ea9ba3543c79c5f0f29c3166494b1d083f044' 
  AND token = 'INSNmPP/3Pfp29sex6oO15bYqvsZiiQCB98NdVeeY2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}