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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56153ed9fc8f4e5792d978b6191df05b5a67e66ad5d489d00e55d22fa6218cfc' 
  AND token = '5QV6uw6y/40aQJoRPQRZyjEWVgRGSrii/t6Oy8dQHUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}