SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d8ee0603b7c2bf0b8e9740288df9ab4091505f14d4fdf08925e427e07b3ebb9' 
  AND token = 'kAlVUaU3h+SJCo9EqidBQ/NRN+4+9gAYoUZlXJSPDnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}