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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b35e0460b7e5dbde35181fe503b922b034afe18d23b00ecb535c5bb7cd5111' 
  AND token = 'cB/wfHEpmYtmNnuaU7hnkHfpFuzYGTBeq0QEiz4UK8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}