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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c1c4d266e2c503a8731e5187b421ab5aef23e3e6b69be7f8fdcdd02014c0b81' 
  AND token = 'ixQBxmX4CltusBql0pw2G+SnDrKTvbqnKMf/axTZ9Nk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}