SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89e48cad402f94370dc49169566a6550da7648ebbbeb0a9a928a099b7bc8d0bd' 
  AND token = 'scfJcNTOMaRojPEKDYwSWsL880IP9dvpIRER/cnaDhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}