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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2b2dd0be843e632212b40e46223c3fd9a442a0f5432b4daf32f89412ac70de4' 
  AND token = 'PTshIv0Q3Z14iOw9uAtbTBEEVQWe8fY6O2xaMSGVVBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}