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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6371e6ab2f41c431dd0fec4cc8246973ecbded8b1c5f648b639f038873c0f022' 
  AND token = 'r2gT1ceB4opyVDhQOtRm9oUaf/rTNV+hX+r4FMayaIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}