SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b3eea366ad3d3f132fe88f34a98f1da3f63db89ad0548e00eef2f3e8bff8ff' 
  AND token = '8yfcOXFvX70ceS4I2AjigQz6W0bd6ZI3+EDFeZnMtFw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}