SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52d539e09dbffd9db68cd9a08887eebee46336ddab021770f8b63cfef8451b30' 
  AND token = 'RelkwoIdD6Vdy/WnR3jyaBUgt3oWZhs6Jwl6vQBmoTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}