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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6d50b782191b6d1394c1db5c3654c639d7b4cc2baa3ed6b6427fce2c3af251f' 
  AND token = 'A0V8jzmUykikugMuo6U2N3XVaVOYtmMQNZRfDwGTwWk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}