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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77e5de82a72da1d65203fb0469e2dea48fad8978fea293ef35e71a662149b400' 
  AND token = 'WhTPF8mkF2IxB+lnxBc8PyBY/za4N3DamgyLXCC3gjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}