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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27fc0454dcd334c3c5f9ffdee3d5a4988401d1e22b4cc8131d6e204ce969af97' 
  AND token = 'sexYRU4yfl3pRedGmDvkwLiipBNT38SJ5a9HXcH7zAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}