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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc51a590dd2cd71a01ddbaadaeaf5f175a6b4b5ca25d8e02795510a6dace21a' 
  AND token = '3mD0xWByNEqIZeTMxou7QD++iaqtohJKDaH9lticX88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}