SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7485bae87e751463b8b16d31e369a4eff1ce54ec5a613d7fec2cfce32626fd78' 
  AND token = 'q6M/Ne2BO+20LwJsr0LJrm+w8VyeGo7rZ0rtjlBqVTE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}