SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b380ae66d5195a652ab5ed7950e4827a299b89b592d8ba56f194ca4c2be8b042' 
  AND token = 's5cpjYtMLFEGEcgcsiEuoBh+ptXNpeD03Pr98vNwOEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}