SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57d77159b33fefc3b86486e7d4fade6fe16de4f15c6d2689ff1c27f0115ddd16' 
  AND token = 'WXODkuOEacMp3Sw4t4ZZbe6qvb3CHC17KbKIwe5yYHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}