SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '789fcbfbb24e478202aaa79b863e77d300501b8a8a51a1a4b6ca2e9ffcb52d20' 
  AND token = 'cL37JCHGcEJMBbr1GNThKE/7jeFb/HB5qynuu9MId7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}