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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7eacee169f306f648e1e812a37366ccff3543b6ed38f3e0dd07358ae727d7f9d' 
  AND token = 'l69A1bQCiJc1eUQ19SsO7M9wvqLbu66WD27IJEk8F00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}