SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65b6ea6e8d1456f6e1e241de67f4a1986e9ca1ce5afe4343ca6320d5550362a3' 
  AND token = 'M7K8dTXMI57+4Go/UBpgB0hEt8QhOquwe4DkWI3/XFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}