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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3ff6c66393f0739ed83cc561569d9f44062fe8eee9f70c0488e690b2ba8d081' 
  AND token = 'uXb+477TuqOOTtBZ3+/BQKhE3+mrIVxngTBDbbuX3Rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}