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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ceab651cd9b1cb9e4d25c9d00342f857f4346a7b6400588b10434ad64338946' 
  AND token = '3DXESfF71UBndfOw8utOg6vXocrg7N4VC/OJqdIctD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}