SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '792aebcaa8449610038e1a5f3e153818e83239a8d2b65e76d5e3d541a54537d4' 
  AND token = '/IIKVwCPBrJuSR1gSweboffnULj6xi6lWvaFDTlOQ64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}