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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66603d2e7e9ccd1a7aeb2975ee58c943a8163202ad9d6b1b978e1719641ded1' 
  AND token = 'NIsSEVzEDFpPiiXHhnpEBZOjXsMSR7A8YqS2Tm/umNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}