SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3df62b9dcd97781ac30075d96696e5ae6043c58fa97f9f2ad52ffa4bb4e01083' 
  AND token = 'BrGLxR4uSaCgzquFz5DRdv1s3HBYoHQpL3kzFd9LBdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}