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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25701a14a1bf1901e50d41085ef4ebc825a530b547e5426a693ed02434af2fb8' 
  AND token = '88f6vhY5gqofa4OZx7yMNM80tgoII9rCQjzTSB6Xv50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}