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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f590fc020e00e26cd254ba39eb706f733bea7a12122d9ca423b17bb07f2fac57' 
  AND token = 'ti2h7vUJQ6ykyH/MhyT3oq0NUwPnKzQqtyGy+cR3TiU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}