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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed8fb6508b350323331378451a642418e98cbbe0cc112d5a0c6e4d1e3bf94236' 
  AND token = 'VP/R8t94KsCaxh2iI0fsYTvt4yI6MZxvBsZBhLswgSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}