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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b898396813750a139d230d004397e8ded7d2dc8fb4c5d4be857b39cce29100a8' 
  AND token = 'MHYraha4C5mhwfD2gw1R4XklnXAPAJ+JTp39mwBKDDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}