SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6a5487aedb358358b9ed0c7fe26a5c0ae7c5c6f009c7f4db7c3098a28714764' 
  AND token = 'ayb61X4JRrBHm0my9rHIQL/s/1azYo4SGz3TXDX6qVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}