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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3e66c285a661a668fd5f0c715e1bd86aae7fc51534f10864dc5643ebb15b27f' 
  AND token = 'D0KHymxFXyvZtVKmBX+LB3i9iXpdTzxmJJNP2t4MDuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}