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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27c8aabb4b5ba6f9c8714fec6e1de7d2308872a2234c1c60e84e53133ecf95e5' 
  AND token = '5S3JASerYIH/h8+QlRUkYCMQR4l8dcfU9qO5NbHEZdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}