SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de205d84bf1aff7e450abb9fba2cf8c03abccc0fa6e3396602d6613670cd166' 
  AND token = 'qSE+YBCglG/YOT7eZSYwg3qJ04wBrJ8e4cyXN9784eA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}