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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a52dbe00380321991627b46451d2f488aab1351c79d4bf6a76e4d9ce31ea721' 
  AND token = 'My+T4shhQkpyBfZz8fZC1zIqrRfEGUOnXrhSX4CRmho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}