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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00d497d84929302ff1f37822292fbbe1320cf3845b5979ca1e8a6ad3a82d098d' 
  AND token = 'wwbkSN0Q0LUGElFoBC2jiaKiEwZvna+O3gZdEZsHcWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}