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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0edfbb4e7f0667fd306c29860661aa495322eca69a8f3be45490913e4c22af68' 
  AND token = 'R3m2k4QmZ23LMIRNcAOIWouj/O+fKD7yZXXy3Zf7gns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}