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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e48a504c3a4917255d449ac15a8c2fbeab9ef357551aad2fafa739b27f17531' 
  AND token = 'HdQyeRWBrXzVVG6iHPMI/Scz0+0eovSnyTHlOv+fV/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}