SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f12ad6f98a8ffb567324798ee2cff00283739121b04e94b8c5f0b703522335ec' 
  AND token = 'MFEPHZ1T58e/P4qsHOeCDSvwHWzeq04O/WpaF6kIapg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}