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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b280c0b3281c87bba91db27a986d9d42a4674ecc91d44115dce997d4c5493de' 
  AND token = '+nvhXg3UJOod5PaNV1Rgil/7ivggtlsd/F0WG+o9jL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}