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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f468919db978ac9f4f58abf3dc52a4a1b4ed0099255a61a71feb928eb4b7f420' 
  AND token = 'wP4YNy6hi7t5i/iGEkAsiVKtWe2e8BN3GbNb+rhCKRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}