SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354f92657619e2fdd40c561339d12edff107daeb394e28ba0b0521c74538b41d' 
  AND token = 'rHQphDM2ph93i7k+ulISXodR9G7h/3PqxzEQCU9MxWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}