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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6759affdb4684f7185780ebfa210e26a9663cd230d740aa07d28d3a2faf1f190' 
  AND token = 'nk8Ndek6ssHyhUguMkFMt7hZKZrKB2xcb4kVPrsVxP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}