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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4769ca0ab2212b4ed006ed1b3c8bf23bf09526c69868a31ebac718acf4b59774' 
  AND token = 'QVsQzMPcql1EvFk5zHGjc7+OkALWu0uz454lExkQlkQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}