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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cb81022353527e7cb59d4eeb97f45d44bc1ed7b48e2bda86233a2b56bab4b41' 
  AND token = 'EbAusNTTHv5hbAw2ywbSwG2HzDetkA+H+SkzqzOnX4g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}