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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b527298db333a6cf1ccf1ebe7bd719c8e50e82e094a04debd993ff1b99f6bfb9' 
  AND token = 'Sx57ug5uc+21ZPUVZbzMLQxxKyASfcf02L2FMXVDI9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}