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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad19883f05fa96a41a2f22cf91537abb5ba1c5f977c2090829fa93d84cd90ab5' 
  AND token = 'p/gdNE4WVKjkk4t5/4f0YE4K6ZE1OFv5n4xf3BGOuzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}