SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a75d6070bb2d5a0ae612ab573a7101d8971aaa0152d1d00ad358c9c85783558' 
  AND token = 'XzyUK8HOZMB0wTDdcQKPBRnQCest86ucCn1oT16Lw0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}